Merocil (Meropenem) Injection is a High-potency antibiotic for life-threatening infections. Buy now!
🦠Merocil Indications:
Merocil is one of the most powerful antibiotics that helps patients recover from serious diseases when used. It is safe, administered intravenously, and prescribed by hospital doctors after consultation. Meropenem is only used when other antibiotics do not work against bacteria or bacteria are very powerful and hard to kill.
🧊 Meropenem 1gm is used to treat the following diseases, and the medicine is used for people of all ages as needed.
🔹 Acute pneumonia and lung infections
🔹 Urinary tract infections (UTI)
🔹 Intra-abdominal infections such as peritonitis
🔹 Skin infections or infected wounds (For example, diabetic foot)
🔹 Infections in the joints and bones
🔹 Infection of the blood (sepsis)
🔹 Infections in the weak immune patients (like, after chemotherapy)
🔹 Infection of the meningitis in the brain and spinal cord covering.
🔬Merocil Pharmacology and Mode of Action:
Merocil is the most powerful medicine. It is a broad-spectrum carbapenem antibiotic Which completely disrupt the structure of the bacterial cell wall. As a result, bacteria lose their personal pathogenic ability. And it inhibits the formation of peptidoglycan by attaching penicillin-binding of proteins (PBPS). Which is crucial for the life of bacteria. As a result, bacterial cells are destroyed. Merocil injection is active against both Gram-positive and Gram-negative bacteria. As well as multidrug-resistant strains. It is stable In Opposition to most beta-lactamases enzymes. Thereby more Increase its effectiveness. After intravenous administration, the body rapidly absorbs Meropenem into the blood and tissues, and then the kidneys properly remove it from the body.
💉Meropenem 1gm Dosage Guide for Merocil Injection:
Merocil is the most powerful antibiotic that is used to treat serious infections caused by the bacteria. The dosage of this medicine depends on the patient’s age, weight, the type of infection, and kidney function.
Meropenem Dosage for Adults using Merocil Injection:
Merocil (Meropenem) children’s dosage:
🔹 For a normal infection, 20 mg/kg is enough.
🔹 In a brain infection as like meningitis, 40mg/kg is given.
🔹 The dose should not go beyond 2 gm at one time.
🔹 If the child’s weight is more than 50 kg, the meropenem IV injection dose is given as in adults.
Pediatric Dose of Merocil Injection: Meropenem Dose in Neonates
Physicians use Merocil 1gm injection very carefully for neonates under 3 months of age. They usually administer the drug every 8 to 12 hours at a dose of 20 mg/kg.
🔹 In the premature babies, the kidneys work gradually, so the interval between doses is longer.
Kidney Problems: A Meropenem IV Dose Adjustment
Example: At that time, if doctors find out that the patient’s kidneys are not working very well, Doctors may prescribe a dose of Merocil 500mg once a day. In ongoing dialysis patients, Doses are given after each dialysis session according to the advice of a consultant.
Liver Problems and Meropenem Injection: Merocil 1gm Dosage Consideration
No need to change the dose of Meropenem for liver problems, because it comes out from the body through the kidneys.
❗Important Tips: Using Meropenem (Merocil Injection)
Without a specific disease, Meropenem can not be used. According to the advice of a doctor use only. It is very important to check the infection test before using Merocil because experts have to ensure whether the disease will be restrainable by this Meropenem injection. Regular monitoring is crucial for patients who have kidney and neurological problems. First, the injection dissolves properly. Then, using a new syringe, administer it intravenously (IV); in that case, the Meropenem injection will work effectively.
🚨Some Symptoms Of An Overdose: Meropenem Injection
Due to an overdose of the carbapenem antibiotic IV injection, the patient’s body may show different effects. Some of these are serious; please you continue reading the details below:
1. Unusual Neurological Symptoms:
Problems Of Spasms: The risk of spasms may increase because of an overdose of Merocil 1gm vial injection, Especially in patients who have kidney problems.
🔹 Disorientate: As a result of an overdose, disorientation and mental confusion may appear.
🔹 Tremor: Patient’s hands and feet may tremble uncontrollably.
2. Some Gastrointestinal symptoms:
Intense diarrhea: Due to an overdose, severe diarrhea may appear, like watery or bloody stool.
🔹 Dizziness, Vomiting, or Nausea: These general symptoms are related to an overdose.
3. Several Skin Reactions: These may appear like skin blisters or red spots.
🔹 Itching and Irritation: Patients may feel itching or irritation all over the body after taking an overdose of Meropenem.
4. With other issues:
🔹 More headaches: Because of the overdose, the patients are likely to have more headaches.
🔹 Lightheadedness: The people who have consumed an overdose may feel mild vertigo and imbalance.
🚨Instant Actions to Take After a Merocil Overdose:
An overdose is suspected:
The patient has to take medical treatment: Immediately go to the nearest hospital or contact your doctor.
Do not take medicine arbitrarily: Patients have to avoid taking arbitrary medicine without a doctor’s prescription.
Inform All Symptoms: You must inform the doctor about all your physical symptoms for a complete diagnosis and proper treatment.
🤰Precautions For Pregnant Women:
🤰Meropenem While Breastfeeding:
For Meropenem, doctors usually consider it safe during breastfeeding. This medicine may pass into the breast milk in small amounts, but it does not significantly harm the infant’s body. Therefore, a qualified physician should supervise its use while using the drug.
🔹 According to FDA And WHO Guidelines: The FDA Pregnancy Category: B- there is no evidence of risk from studies on the human body, but patients should take maximum caution.
🔹 WHO Listed Essential Medicines: For the treatment of severe infections, for example, sepsis, meningitis, and gastrointestinal infections.
🔹 Dose Adjustments: The Meropenem dose should be reduced for the patients with kidney problems (CrCl <50 mL/min).
🌍Meropenem Scientific Studies:
1. According to the 2019 Study In Antimicrobial Agents and Chemotherapy:
🔹 Merocil is more than 90% effective against multi-drug-resistant “MDR” infections.
🔹 Since it is bound minimally to plasma proteins (~2%), it allows better penetration into tissues.
2. According to the NEJM Clinical Trial 2021: if Meropenem and Vancomycin are used in combination in patients suffering from septic shock, then the survival rate increases.
⚠️Some Safety & Side Effects:
1. Common Side Effects (%): Diarrhea (8%), nausea (3%), and rash (2%) may appear in patients.
2. Serious Risks: an overdose of Meropenem may cause seizures, C. difficile infection, as well as allergic reactions.
3. The Black Box warning: there is no black box warning for Meropenem, but antibiotic resistance is a global issue.
👨⚕️The Expert in Clinical Guidelines for the Use of Merocil Injection:
🔹Based on the findings and guidelines, the Infectious Diseases Society of America (IDSA) has designated Merocil as the first-line antibiotic for the treatment of hospital-acquired pneumonia (HAP) and complicated urinary tract infections (UTIs). Doctors often observe that resistant bacteria are causing these dangerous infections inside hospitals.
🔹 Health authorities in the Bangladesh National Clinical Guidelines strongly recommend using Meropenem only for patients in the intensive care unit (ICU) and in life-threatening or serious infections. An overdose may lead to increased antibiotic resistance, in the future, which may become a major challenge for effective treatment around the world.
🧊 Meropenem Broad-Spectrum Antibiotic Storage Systems:
It is crucial for properly storing to maintain the quality and efficacy of Meropenem.
1.🔹Store the powder at natural room temperature
2.🔹Use it immediately after reconstituting the medicine:
3.🔹Meropenem Storage Instruction:
√ If the merocil is not used right away, The mixed solution can be stored in a refrigerator at 2°C to 8°C for up to 24 hours.
4.🔹Avoid Deepfreeze
5.🔹 Keep out of reach of children.
√ Always keep Meropenem in a location inaccessible to children.
6.🔹Follow the expiration date
√ Pay attention to the expiry date printed on the vial before using Meropenem.
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